Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia (NCT05982015) | Clinical Trial Compass
CompletedNot Applicable
Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia
China1,651 participantsStarted 2024-01-22
Plain-language summary
Verifying whether remote ischemic adaptation can reduce the occurrence of stroke related pneumonia in acute stroke patients within 24 hours of onset
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age≥18 years old;
* Diagnosis of acute ischemic stroke;
* Remote ischemic conditioning or sham-remote ischemic conditioning can be treated within 24 hours after stroke onset
* NIHSS score≥4;
* Subject or his or her legally authorized representative was able to provide informed consent.
Exclusion Criteria:
* During the screening period, body temperature ≥ 38 ℃;
* Evidence of lung infection, urinary tract infection or other infectious diseases during the screening period
* Expected lifespan less than 7 days
* Mechanical ventilation is expected to be required within 7 days;
* Anti-infective drug were used within 7 days prior to stroke;
* Uncontrolled hypertension with medication (defined as systolic blood pressure ≥200 mmHg and/or diastolic blood pressure ≥110 mmHg);
* There are contraindications for remote ischemic conditioning (such as skin and soft tissue injury, fractures, peripheral arterial disease, etc. in the upper limbs);
* History of autoimmune disease or malignancies;
* Use of immunosuppressive drug within the preceding 3 months;
* Pregnant or lactating, or pregnancy test positive;
* Current participation in another investigational trial;
* Other conditions are not suitable for this trial as evaluated by researchers.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.