Acute Effect of Osteopathic Visceral Mobilization Techniques
Turkey (Türkiye)20 participantsStarted 2023-08-07
Plain-language summary
Multiple Sclerosis (MS), caused by lesions in the white matter of the central nervous system, is an autoimmune inflammatory demyelinating chronic disease.
The disease may present with many findings from fatigue, spasticity, balance and gait disturbances to bladder-bowel dysfunction (Ferreira, A.P.S., et al., 2019). When the rehabilitation methods for incontinence were examined, pelvic floor muscle training, tibial nerve stimulation and sacral neuromodulation were frequently encountered (Rahnama'I, MS., 2020). Pelvic floor muscle training should create an effective result in MS patients, and the training should be done for a long time, such as 8-12 weeks. No study has been found examining the effects of manual therapy techniques and diaphragmatic breathing exercise in the acute phase in functional or neurogenic bladder-intestinal dysfunctions.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of Multiple Sclerosis
* The age of 18 years and the older
* Individuals with stable medical condition
* Having complaints of urinary dysfunction for at least 6 months,
* Mini Mental test score \> 24 points
* EDDS less than 6.5 (0-6.5 points will be)
* Volunteering to participate in the study
Exclusion Criteria:
* Having cognitive problems
* Presence of pelvic organ prolapse or prostate
* Pregnancy
* Abdominal surgery history
* Presence of urinary system infection
* Continuing drug use for overactive bladder
* Having received pelvic floor muscle training
* Concomitant other neurological or kidney disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Spasticity Assessment
Timeframe: Change from MAS scale at one week
2
Evaluation of Pelvic Floor Muscle Activity
Timeframe: Change from Muscle Activity scale at one week
3
International Consultation on Incontinence Questionnaire Short Form ICIQ-SF
Timeframe: Change from ICIQ-SF at one week
4
Constipation Quality of Life Scale: Constipation Quality of Life Scale (CIQS)