The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency … (NCT05980221) | Clinical Trial Compass
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The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
United Kingdom150 participantsStarted 2020-08-24
Plain-language summary
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
Who can participate
Age range16 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria: (for main pancreatic cancer cohort)
* PDAC
* PEI (as defined by breath test)
* Tolerating oral diet Inclusion Criteria: (for CF cohort)
* CF
* PEI (as defined by breath test)
* Tolerating oral diet Inclusion Criteria: (for CP cohort)
* CP
* PEI (as defined by breath test)
* Tolerating oral diet
Exclusion Criteria (all arms):
* No other GI conditions
* For each arm no evidence of the other arm conditions
* For health controls, no history of CP, CF or pancreatic cancer
* No GI surgery (except pancreatic resection in the pancreatic cancer cohort)
* Unable to consent
* Unable to travel to UHB for testing
* Prognosis \< 2months
* Performance status 2+
What they're measuring
1
Metabolome
Timeframe: 1 year after study completion
Trial details
NCT IDNCT05980221
SponsorUniversity Hospital Birmingham NHS Foundation Trust