Medical Stone Expulsive Therapy for Acutely Obstructed Ureteric Calculi

Inclusion Criteria: * Adults male and female aged 18 to 70 years * Patients who give informed consent * Stone located in the distal 1/3rd of ureter (Single, unilateral and radiopaque ureteral calculus 5 to 10 mm visible on the CT-KUB± X-ray KUB within the ureter * Serum creatinine level within the normal range (adult men, 0.74 to 1.35 mg/dL \& 0.59 to 1.04 mg/dL) * Ability to tolerate oral fluids and oral pain medication Exclusion Criteria: * Patients already taking an alpha-adrenergic antagonist medication for 4 weeks * Evidence of any other renal stone simultaneously present or at any location * Hydronephrosis Grade 3 (Moderate) \& Grade 4 (Severe) Patients with eGFR \<60 ml/min/1.73m2 * Signs of infection including temperature \>38ºC or Urinalysis with any of the following: Positive Leukocyte Esterase, Positive Nitrates, or White Blood Cell Count \>5/hfp in the setting of a positive urine culture (defined as a single isolated bacterial species population of \>100,000 CFU) * Patients with chronic pain already undergoing treatment with narcotic medications or drug abusers * Pregnant or lactating women * Patient suffering from urinary tract infection, ureteral surgery, and existing DJ stents. * Clinical jaundice * Any forms of anatomical obstructions in the urinary tract * The previously suffering from postural hypotension * Any other disease jeopardizing participation in trial and could lead to increase patient health risks * History of allergic reactions with the study d…