The goal of this study is to evaluate the capacity of allogeneic bone marrow mesenchymal stromal cells (MSC) to induce bone regeneration in patients with periodontal disease. MSC cultured are loaded on a collagen scaffold, included into autologous platelet rich plasma clot and implanted in the bone defect.
Age range
18 Years – 65 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in clinical attachment level (CAL)
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation
Change in probing pocket depth (PPD)
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation
Gingival recession (GR)
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation
Change in bone density
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation
Change in Tooth Mobility (TM)
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation
Change in bone depth
Timeframe: Follow-up includes evaluation at 3, 6, 9 and 12 months post-transplantation