Detecting Otoconia With CT-Scan (NCT05969340) | Clinical Trial Compass
WithdrawnNot Applicable
Detecting Otoconia With CT-Scan
Stopped: The study is still in the planning stage, undergoing protocol reconsideration.
0Started 2023-11-01
Plain-language summary
Benign Paroxysmal Positional Vertigo (BPPV) is a benign inner ear disease that causes the patient to experience short episodes of vertigo when there are changes in head position. The current theory on the causes of BPPV is the displacement of the otoconia from the otolith organ to the semicircular canal organs. BPPV's current treatments consist of repositioning maneuvers to readjust the location of the otoconia back to its original place. Even though the treatments are highly successful in many cases, this study, if proven successful, will help confirm this theory and will help diagnose complicated cases where BPPV is recurrent and treatment has been unsuccessful.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Experimental Group:
* Diagnosed with Posterior canal BPPV.
* Age 18 or older.
* Clear nystagmus consistent with canal direction and stimulation.
* Mild or greater complaints (none, mild, moderate, severe).
* Crescendo decrescendo nystagmus pattern.
* Slow phase eye velocity ≥ 15 deg/sec.
Control Group:
* Scheduled for CI implantation CT scan.
* Age 18 or older.
Exclusion Criteria:
Experimental Group:
* Anterior or lateral canal BPPV.
* Inability to undergo CRM and DH maneuvers.
* Central vestibular disorders.
* Multi-canal BPPV or subjective BPPV.
* Pregnancy.
Control Group:
* BPPV, central vestibular disorders, multicanal BPPV, subjective BPPV.
* Ossifying labyrinthitis, DFNA9, obstructive vestibular schwannoma on MRI.
* Normal VHIT or history of meningitis.
* Pregnancy or other vestibular pathologies.
* Past history of BPPV.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Visualisation of presence or absence of otoconia in the posterior semicircular canal by comparing patient with confirmed BPPV symptoms compared to control subjects without BPPV