Optimizing Phototesting and Investigating Photobiology of Visible Light

Inclusion Criteria: * Healthy individuals age 18 and older * Fitzpatrick skin phototype (SPT) I-VI, 7 with SPT I-III and 7 with SPT IV-VI, with normal healthy skin * Able to understand the requirements of the study and its associated risks * Able to complete and sign a consent form * Willing and able to refrain from any medications or herbal supplements during the duration of the study, unless permitted by the investigator * Agrees to refrain from using any new topical skin care products, laundry detergents, or fragrances while participating in the study * Has not had excessive sun exposure for 7 days prior to enrollment in the study Exclusion Criteria: * Recent history of vitiligo, melasma, and other disorders of pigmentation with the exception of post-inflammatory hyperpigmentation * History of relevant skin conditions such as atopic dermatitis, eczema, or sunburn on any part of the body * History of photodermatoses or photosensitivity disorders * History of melanoma or non-melanoma skin cancers * Use of tanning parlors or exposure of the irradiated sites to sun light during the duration of the study * Use of topical or systemic treatment that is likely to interfere with assessment, study results, or pose safety concerns * Subjects with a tendency to bleed excessively * Known allergies to anesthetics (lidocaine) or anaphylaxis treatment (epinephrine) * History of hypertrophic scarring or keloid formation * Use of any photosensitizing medication within the visible light r…