CompletedNot Applicable

Cardiac Management of Patients With Thalassemia Minor and Breast Cancer

Turkey (Türkiye)26 participantsStarted 2020-01-01

Plain-language summary

This retrospective study aimed to evaluate the demographic characteristics, clinical conditions in term of physical examination findings), functional status, and laboratory results of patients with thalassemia minor (TM) and breast cancer (BC) in order to identify any differences between the group with BC only. Available data as anticancer treatment, comorbidities, weight and height will be combined to report body mass index (BMI) in kg/m2, systolic and diastolic blood pressure, heart rate, ECG, transthoracic echocardiography, blood count, lipid panels, glucose, kidney function tests, (N terminal) NT-proBNP, troponins, handgrip assessments, functional status were extracted from patients files and hospital electronic archives.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients with diagnosis of breast cancer, and thalassemia minor,
✓. \>18 years old,
✓. Referred by oncologist for cardiac evaluation.
✓. Patients with available cardiac evaluations data at baseline and during breast cancer treatment

Exclusion criteria

✕. Patients without diagnosis of breast cancer, and thalassemia minor,
✕. \<18 years old,
✕. Patients without any cardiac evaluations at baseline, and during cancer treatment.
✕. Patients with history of any cardiotoxic treatment prior to enrolment.

What they're measuring

Incidence of any rise in troponin

Timeframe: From enrollment to 12 months

Incidence of any rise in NT-ProBNP

Timeframe: From enrollment to 12 months

Incidence of any reduction in LV

Timeframe: From enrollment to 12 months

Trial details

NCT IDNCT05960214

SponsorIstanbul University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-22

View on ClinicalTrials.gov More Breast Cancer trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients with diagnosis of breast cancer, and thalassemia minor,
✓. \>18 years old,
✓. Referred by oncologist for cardiac evaluation.
✓. Patients with available cardiac evaluations data at baseline and during breast cancer treatment

Exclusion criteria

✕. Patients without diagnosis of breast cancer, and thalassemia minor,
✕. \<18 years old,
✕. Patients without any cardiac evaluations at baseline, and during cancer treatment.
✕. Patients with history of any cardiotoxic treatment prior to enrolment.