Knee Osteoarthritis, Aging and Metabolic Syndrome

Inclusion Criteria: * Patients who met the American College of Rheumatology (ACR) clinical criteria for knee OA and had symptomatic OA of at least 1 knee (index knee), with a Kellgren / Lawrence (K/L) score ≥ 1 in that knee Exclusion Criteria: * Any patient with a history of trauma to the knee * Any other form of arthritis (e.g., rheumatoid arthritis, seronegative spondyloarthropathies, gout, pyrophosphate disease, or other crystal arthropathy)