The goal of this study is to evaluate the efficacy, safety, and tolerability of enlicitide decanoate in adult participants with heterozygous familial hypercholesterolemia. The primary hypothesis is that enlicitide decanoate is superior to placebo on mean percent change from baseline in low-density lipoprotein cholesterol (LDL-C) at Week 24.
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Mean Percent Change From Baseline in Low-Density Lipoprotein Cholesterol (LDL-C) at Week 24
Timeframe: Baseline and Week 24
Number of Participants With Adverse Events (AEs)
Timeframe: Up to 64 weeks (8 weeks postdose)
Number of Participants Who Discontinued Study Drug Due to an AE
Timeframe: Up to 56 weeks