CompletedNot Applicable

Intravenous Lidocaine to Reduce Propofol Consumption During Gastroscopy.

Belgium46 participantsStarted 2023-07-21

Plain-language summary

The goal of this clinical trial is to assess if intravenous administration of linisol reduce the propofol consumption and the sides effects of sedation during gastroscopy in healthy patients (ASA 1 and 2 patients). Prior to propofol sedation, participants will receive either an intravenous bolus of linisol (1.5 mg/kg) = treated group or placebo = control group. After the gastroscopy, patients will be asked to complete a satisfaction questionnaire

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients scheduled for gastroscopy under narcosis and who have signed the consent. * ASA score: 1 and 2 * BMI between 18 and 30 kg/m2 Exclusion Criteria: * Lidocaine allergy * Anesthesia within the last 7 days * Use of local anesthesia in the last 24 hours * Rhythm disorder or HR \<50 * Pregnant women and breastfeeding * Participation in another clinical study in the last months * Cannot understand VAS score or French * Severe central nervous disease and mental illness. * obstructive sleep apnea (known or STOP BANG score \>5) * Upper lung infection. * Liver or kidney function disorder

What they're measuring

total propofol dose in milligramme

Timeframe: procedure (from the beginning of propofol infusion until arrival of the gastroscope in the stomach)

total propofol dose in milligramme

Timeframe: Procedure (from the beginning of propofol infusion until endoscope removal)

propofol in site effet concentration in microgram per milliliter

Timeframe: procedure (from the beginning of propofol infusion until arrival of the gastroscope in the stomach)

propofol in site effet concentration in microgram per milliliter

Timeframe: Procedure (from the beginning of propofol infusion until endoscope removal)

Trial details

NCT IDNCT05944887

SponsorErasme University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-21

View on ClinicalTrials.gov More Diagnostic Gastroscopy trials

Plain-language summary

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

total propofol dose in milligramme

Timeframe: procedure (from the beginning of propofol infusion until arrival of the gastroscope in the stomach)

total propofol dose in milligramme

Timeframe: Procedure (from the beginning of propofol infusion until endoscope removal)

propofol in site effet concentration in microgram per milliliter

Timeframe: procedure (from the beginning of propofol infusion until arrival of the gastroscope in the stomach)

propofol in site effet concentration in microgram per milliliter

Timeframe: Procedure (from the beginning of propofol infusion until endoscope removal)