Active — Not RecruitingNot Applicable

Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUD

United States27,257 participantsStarted 2023-03-29

Plain-language summary

The goal of this multi-site observational cohort study is to link electronic health records (EHR) with novel data sources to examine insurance instability and its association with all-cause and overdose mortality in adult patients who received medications for opioid use disorder (MOUD). The main objectives of the study are: * Objective 1. Perform data linkage of a cohort of patients who received MOUD with the National Death Index using a probabilistic algorithm for matching records to ascertain fact and cause of death relative to treatment and insurance status. * Objective 2: Assess the association of insurance instability and risk of death, including all-cause mortality and drug- and alcohol-related overdose mortality.

Who can participate

Age range16 Years

SexALL

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The retrospective cohort study will consist of patients 16 years and older who received MOUD between January 1, 2012, through December 31, 2021, with follow-up through December 31, 2022. Evidence of MOUD will be determined by (1) buprenorphine with or without an OUD diagnosis and (2) naltrexone (injectable extended-release (XR) or oral; oral naltrexone is included because it may be prescribed prior to the transition to XR naltrexone) with an OUD diagnosis from pharmacy dispensing or orders data.

What they're measuring

All-cause mortality

Timeframe: January 1, 2012 - December 31, 2022

Drug and alcohol-related overdose mortality

Timeframe: January 1, 2012 - December 31, 2022

Trial details

NCT IDNCT05944133

SponsorKaiser Permanente

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-02-28

View on ClinicalTrials.gov More Opioid Use Disorder trials