Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE

Inclusion Criteria: Participants will be included in the study based on the following inclusion criteria: * Older men and women between 60-80 years * The presence of sarcopenic obesity was considered when the following two conditions were satisfied: Fat mass \> 34.8% and FFM \<90% of subject's ideal FFM. * Resident in Verona (Italy) * Stable weight in the previous 2 months * Previously sedentary (less than one hour of exercise per week in the last 6 months) * Signing of the informed consent for participation in the study Exclusion criteria: * Unstable angina or recent myocardial infarction * Malignant or unstable arrhythmias * Heart failure NYHA class \> II * Severe respiratory failure * Severe heart valve disease (i.e severe aortic stenosis or insufficiency) * Abdominal and/or thoracic aneurysm * Recent intracerebral or subdural haemorrhage * Poorly controlled arterial hypertension * Presence of pacemakers or metal prostheses * Severe chronic renal failure * Symptomatic musculoskeletal pathology * Symptomatic disc herniation, arthrosis, acute joint, tendon and ligamentous injuries, hip and/or knee prostheses recently placed (\<6 months) or with joint instability, symptomatic or large inguinal or abdominal hernia * Acute retinal detachment or bleeding * Recent eye surgery (laser, cataract, retinal surgery, glaucoma surgery) * History of malignant cancer within the previous 5 years * Diagnosis of dementia * Eating disorders