Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

Inclusion Criteria: * Participants must be 18 years of age or older * Participants must have previously been diagnosed with head and neck cancer and undergone surgery and radiation as part of their standard-of-care treatment plan * Participants must be ≥ 4 weeks but less than 3 months post-radiation therapy at enrollment * Female participants of childbearing potential must have a negative urine pregnancy test ≤ 36 hours prior to study drug administration * Female participants of childbearing potential must agree to use a medically accepted method of contraception for a period of one month after each imaging session * Male participants must agree to shave facial hair on imaging days * Participants must be willing and able to independently use the pneumatic compression device at home daily for up to 12 months as directed by study personnel. Exclusion Criteria: * Persons who are pregnant or breast-feeding * Females of child-bearing potential, who do not agree to use an approved contraceptive for one month after each imaging session * Persons who do not meet inclusion criteria * Iodine allergy * Persons with a chest circumference of 150 cm or more * Uncontrolled hyperthyroidism or parathyroidism (for which an endocrinologist recommends against neck compression) * Carotid sinus hypersensitivity syndrome * Symptomatic carotid artery disease, as manifested by a recent transient ischemic attack (within 30 days), ischemic stroke or amaurosis fugax (monocular visual ischemic symptom…