Contrast-enhanced Multispectral Optoacoustic Tomography for Non-invasive Assessment of Diabetic Gastroparesis

nclusion criteria Group 1 * Written informed consent * T1DM diagnosis * Duration of disease at least 5, preferably 10 years with diagnosed neuropathy Group 2 * Written informed consent * T1DM diagnosis * Duration of disease at least 5, preferably 10 years without diagnosed neuropathy Group 3 * Written informed consent from parent or guardian * T1DM diagnosis * Duration of disease at least 5, preferably 10 years with inadequate medication control (HbA1c value \> 8.5 mmol/l) Group 4 * Written informed consent of parent or guardian * T1DM diagnosis * Duration of disease at least 5, preferably 10 years with good medication control (HbA1c value \< 7.5 mmol/l) Exclusion criteria Generality: * Pregnancy * Breastfeeding mothers * Tattoo in the area of the examination * Subcutaneous fat tissue over 3 cm * Known hypersensitivity to ICG, sodium iodide or iodine * Hyperthyroidism, focal or diffuse thyroid autonomy * Timely close treatment to check thyroid function with ingestion of radioactive iodine (within two weeks before or after the study) * Impaired renal function * Taking the following medications: Beta blockers, anticonvulsants, cyclopropane, bisulfite compounds, haloperidol, heroin, meperidine, metamizole, methadone, morphine, nitrofurantoin, opium alkaloids, phenobarbital, phenylbutazone, probenecid, rifamycin, any injection containing sodium bisulfite