The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection

Inclusion Criteria: * Subjects are aged 20-65 years old of both sexes. * Subjects who have bilateral nasolabial folds with 3-4 points of WSRS baseline measurement. * Subjects who are willing to undergo the dermal filling therapy. * The facial skin is healthy, without any disease that possibly interferes with skin aging status assessment, i.e., facial nerve paralysis * The subject is willing to avoid undergoing other cosmetic treatment and surgery for the entire duration of investigation. * The subject is willing to adhere to the protocol and sign the Informed Consent before the investigation. Exclusion Criteria: * Women subjects who are pregnant, breastfeeding, planning to become pregnant, and not willing to take contraception during the trial period. * Subjects with history of allergies to hyaluronic acid. * Subjects with history of allergies to lidocaine or amide-type local anesthetics. * Those who are suffering from immunity related disorder. * Those who are suffering from a mental disease. * Those who are suffering from alcohol use disorder. * Those who have severe heart, kidney, liver or respiratory system disorder. * Those who have localized infection, severe skin disease, inflammation, tumor or other related disease in the nasolabial fold area. * Those with a scar-prone constitution, prone to scar formation, hypertrophic scars or keloids. * Those with coagulation disorder * Patients undergoing anticoagulant treatment or taking non-steroidal anti-inflammatory drug(NS…