Sauna for Long Covid (NCT05931497) | Clinical Trial Compass
RecruitingNot Applicable
Sauna for Long Covid
United States21 participantsStarted 2026-08-01
Plain-language summary
Research suggests that Whole Body Hyperthermia in a sauna-like environment can reduce symptoms related to post-acute sequelae of SARS-CoV-2 (PASC), or Long Covid. The investigators aim to study the feasibility and treatment effect of this procedure for patients experiencing Long Covid symptoms.
Who can participate
Age range18 Years – 65 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. 18-65 years of age
✓. English language proficiency
✓. Ability to provide informed consent
✓. Ability to lie supine (on back) for 2 hours (required for sauna sessions)
✓. Must have had clinically suspected COVID-19 and a positive antibody test or a documented SARS-CoV-2 infection (a positive reverse transcription polymerase chain reaction test) at least 12 weeks prior to Screening (Note: clinician judgment can override lack of positive COVID test with clear Long Covid onset and presentation)
✓. The Patient Reported Outcome Measurement Information System Fatigue-Short Form v1.0 -Fatigue 7a (PROMIS F-SF43) raw score of 21 or greater at Screening (onset of fatigue confirmed post-infection as in other studies of PASC)
✓. Individuals of childbearing potential must use an acceptable form of birth control.
Exclusion criteria
✕. Fatigue for known reasons other than PASC (e.g. longstanding diagnosis of Chronic Fatigue Syndrome pre-dating Long Covid, low thyroid, multiple sclerosis, AIDS related fatigue, mononucleosis), as determined by clinical discretion of study investigators
✕. Known hypersensitivity to infrared heat exposure, significant history of heat stroke
✕. Breastfeeding, pregnancy or planned pregnancy during study
✕. Active suicidal intent
What they're measuring
1
The Patient Reported Outcome Measurement Information System Fatigue-Short Form v1.0 -Fatigue 7a (PROMIS F-SF)
Timeframe: 2-weeks (primary endpoint) follow up at 6 weeks
. History of bipolar disorder, psychotic disorders, eating disorders, obsessive compulsive disorder, and/or substance use or dependence (within the last year), as per the Mini-International Neuropsychiatric Interview (MINI)44
✕. Positive urine toxicology screen for illicit drug use
✕. Any serious unstable medical condition
✕. Inability to fit into the sauna device. Morbid obesity (BMI \> 40) and/or body shape that might increase the risk of cutaneous burning from the device (because of skin being too close to the heat).