Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS (NCT05928754) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS
2,000 participantsStarted 2023-09
Plain-language summary
prospective, cohort, longitudinal, multicenter, non-randomized study of patients with non-infectious posterior segment uveitis or panuveitis, with a group of control patients (scheduled for cataract or vitreoretinal surgery) and constitution of biological collection.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
UVEITIS Patients:
* Adult patients (≥ 18 years);
* Non-infectious uveitis;
* Intermediate, posterior or panuveitis;
* Inflammatory activity requiring treatment with either one or more of the followings:
* Systemic corticosteroids or periocular or intravitreal injections of corticosteroids;
* Immunosuppressants: methotrexate, azathioprine, cyclosporine, etc.;
* Biotherapy: infliximab, adalimumab, tocilizumab;
* Patients with health insurance;
* Written Informed consent obtained at enrolment in the study.
Control patients:
* Adult patients (≥ 18 years);
* Scheduled patients ( Non-urgente procedure) for cataract or vitreoretinal surgery;
* Patients with health insurance;
* Written Informed consent obtained at enrolment in the study.
Exclusion Criteria:
Uveitis Patients:
* Isolated anterior uveitis ;
* Inactive disease defined as:
* Absence of inflammatory chorioretinal and/or inflammatory retinal vascular lesion;
* Anterior chamber cell grade\< 0.5+;
* Vitreous haze grade \<0.5+;
* Pregnant or breastfeeding woman at the inclusion visit;
* Patient under legal protection (" curatelle " or " tutelle ");
* Patient denied freedom by a legal or administrative order.
Control patients:
* Pregnant or breastfeeding woman;
* Unscheduled (urgent) cataract or vitreoretinal surgery;
* Patient under legal protection (" curatelle " or " tutelle ");
* Patient denied freedom by a legal or administrative order.
What they're measuring
1
Imaging database development
Timeframe: 60 months
2
Biological constitution
Timeframe: 60 months
3
medico economic costs estimation
Timeframe: 60 months
Trial details
NCT IDNCT05928754
SponsorCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts