Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS (NCT05928754) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS
2,000 participantsStarted 2023-09
Plain-language summary
prospective, cohort, longitudinal, multicenter, non-randomized study of patients with non-infectious posterior segment uveitis or panuveitis, with a group of control patients (scheduled for cataract or vitreoretinal surgery) and constitution of biological collection.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
UVEITIS Patients:
* Adult patients (≥ 18 years);
* Non-infectious uveitis;
* Intermediate, posterior or panuveitis;
* Inflammatory activity requiring treatment with either one or more of the followings:
* Systemic corticosteroids or periocular or intravitreal injections of corticosteroids;
* Immunosuppressants: methotrexate, azathioprine, cyclosporine, etc.;
* Biotherapy: infliximab, adalimumab, tocilizumab;
* Patients with health insurance;
* Written Informed consent obtained at enrolment in the study.
Control patients:
* Adult patients (≥ 18 years);
* Scheduled patients ( Non-urgente procedure) for cataract or vitreoretinal surgery;
* Patients with health insurance;
* Written Informed consent obtained at enrolment in the study.
Exclusion Criteria:
Uveitis Patients:
* Isolated anterior uveitis ;
* Inactive disease defined as:
* Absence of inflammatory chorioretinal and/or inflammatory retinal vascular lesion;
* Anterior chamber cell grade\< 0.5+;
* Vitreous haze grade \<0.5+;
* Pregnant or breastfeeding woman at the inclusion visit;
* Patient under legal protection (" curatelle " or " tutelle ");
* Patient denied freedom by a legal or administrative order.
Control patients:
* Pregnant or breastfeeding woman;
* Unscheduled (urgent) cataract or vitreoretinal surgery;
* Patient under legal protection (" curatelle " or " tutelle ");
* Patient denied freedom by a legal or administrative order.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Imaging database development
Timeframe: 60 months
2
Biological constitution
Timeframe: 60 months
3
medico economic costs estimation
Timeframe: 60 months
Trial details
NCT IDNCT05928754
SponsorCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts