Solidarity/Tokomeza Ebola Trial

Inclusion Criteria: Phase 1 * Healthy volunteers aged 18-50 years from study communities * Healthy volunteers with a permanent home address * Able and willing to complete and provide written informed consent. In case the participant cannot read or write, the procedures must be explained to him/her and informed consent must be witnessed by a literate third party not involved with the conduct of the study * Participant must pass the informed consent test of understanding (TOU) * Participant must be healthy in the investigator's clinical judgement on the basis of medical history, physical examination, vital signs and point of care tests (where applicable) performed at screening * If female of child-bearing potential and heterosexually active, practice of adequate contraception for 28 days prior to injection, negative pregnancy test on the day of vaccination, and agreement to continue adequate contraception until 90 days after vaccination * Male participants are eligible to participate in the study if they agree to use a male condom during any heterosexual intercourse with a female of childbearing potential until 90 days after vaccination Phase 2 * Healthy volunteers aged 6 years-65 years from study communities. Individuals with comorbidities assessed as stable will be allowed to participate * With a permanent home address * Able and willing to complete and provide written informed consent or assent as applicable. In case the participant cannot read or write, the procedures m…