RecruitingPhase 2

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Brazil74 participantsStarted 2023-11-08

Plain-language summary

The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Hospitalized patients submitted to orthotopic heart transplantation (HT) Exclusion Criteria: * Requirement of renal replacement therapy at the time of HT * Requirement of extracorporeal membrane oxygenation (ECMO) before or immediately after HT * Severe peri-operative mechanical complications * Double transplant (e.g. heart-kidney or heart-lung) * Hypernatremia (Na ≥ 145) * Severe hyponatremia (Na ≤ 120)

What they're measuring

Prevention of acute kidney injury

Timeframe: Days 3 -7 post-transplantation

Trial details

NCT IDNCT05909150

SponsorFernando Bacal

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03

Contact for this trial

Ciro M Murad, MD

+55 31988988843 ciromurad@hotmail.com

View on ClinicalTrials.gov More Heart Transplantation trials