CompletedNot Applicable

Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria

United States312 participantsStarted 2024-12-12

Plain-language summary

The current project aims to improve the well-being of trans and nonbinary (TNB) individuals through an online intervention (Trans Care) targeting the reduction of symptoms of gender dysphoria. The Trans Care intervention will involve the creation of an online intervention comprised of eight modules intended to reduce symptoms of gender dysphoria, increase active coping, and improve the well-being of TNB individuals. Aim 2 is a randomized controlled trial of the proposed intervention and will enroll 260 TNB participants.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Identify as transgender, transsexual, nonbinary, and/or have a transgender history. * Experience gender dysphoria. * Time available to commit to completing a 4-5-hour online intervention and 1-2 hours to complete follow up surveys Exclusion Criteria: * under 18 years old * individual does not identify as transgender, transsexual, nonbinary, and/or have a transgender history * does not experience gender dysphoria * is unable to commit to the time requirements of the study * does not have access to an internet compatible device

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Depression, Anxiety, and Stress Scale (DASS-21) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Gender Congruence and Life Satisfaction Scale (GCLS) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Modified Gender Minority Stress and Resilience measure (M-GMSRM) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Trans and Nonbinary Coping Measure (TNCM) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Alcohol Use Disorder Identification Test

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Number of Days in the Past Week You Consumed Alcohol

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Trial details

NCT IDNCT05903911

SponsorUniversity of Wisconsin, Madison

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-19

View on ClinicalTrials.gov More Gender Dysphoria trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Depression, Anxiety, and Stress Scale (DASS-21) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Gender Congruence and Life Satisfaction Scale (GCLS) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Modified Gender Minority Stress and Resilience measure (M-GMSRM) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Change in Trans and Nonbinary Coping Measure (TNCM) Score

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Alcohol Use Disorder Identification Test

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up

Number of Days in the Past Week You Consumed Alcohol

Timeframe: before and after intervention (participants will have up to 1 month to complete intervention), 3 month follow up