Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories

General Inclusion Criteria: * Ability to read, understand and provide written informed consent * Age between 18 and 60 years * To be sufficiently fluent in German Inclusion Criteria for the PTSD group: \- Current diagnosis of full PTSD according to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), of subthreshold PTSD, as in meeting two to three of the DSM-5 criteria B-E, or of complex PTSD Inclusion Criteria for the CUD group: * Current diagnosis of mild, moderate, or severe CUD according to DSM-5 * Regular cocaine use in the last 12 months and at least one consumption event in the last 6 months Inclusion Criteria for the Clinical Controls (PTSD+CUD group): * Current diagnosis of full PTSD according to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), of subthreshold PTSD, as in meeting two to three of the DSM-5 criteria B-E, or of complex PTSD * Current diagnosis of mild, moderate, or severe CUD according to DSM-5 * Regular cocaine use in the last 12 months and at least one consumption event in the last 6 months Exclusion Criteria for the HC, PTSD, CUD, and PTSD+CUD groups: * Women who are pregnant or breast feeding or intending to become pregnant during the course of the study or within 3 months after * Other clinically significant concomitant disease states, e.g., renal failure (i.e., estimated glomerular filtration rate (eGFR; CKD-EPI) lower than 60 ml/min/1.73 m2), hepatic dysfunction (i.e.…