Cervical cancer screening is important as it enables identification of women at increased risk of the disease, but high-quality diagnostics of screen-positive women and effective treatment of those with precancer are critical in preventing progression to cancer. With the current transition from cytology-based to primary human papillomavirus (HPV)-screening and a growing proportion of HPV-vaccinated women, diagnostics of screen-positive women will become more challenging in the decades to come. Thus, there is a need to explore how to improve diagnostics while ensuring a low number of unnecessary procedures such as colposcopy and the collection of multiple cervical biopsies. The overall purposes are: Purpose 1: To investigate the diagnostic accuracy of cervical precancer when using a colposcopic scoring system in the diagnostic work-up of screen-positive women. Purpose 2: To investigate the performance of a colposcopic scoring system to identify women without cervical precancer in whom collection of biopsies can be safely omitted.
Age range
23 Years – 99 Years
Sex
FEMALE
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Purpose 1: Diagnosis of collected targeted cervical biopsies
Timeframe: When the histological report is available - typically within 12 weeks after the biopsy was taken
Purpose 2: Diagnosis of collected random cervical biopsies
Timeframe: When the histological report is available - typically within 12 weeks after the biopsy was taken