Respiratory Effects of E-Cigarettes in Obese Youth (NCT05869318) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Respiratory Effects of E-Cigarettes in Obese Youth
United States56 participantsStarted 2023-04-04
Plain-language summary
To determine vaping behaviors and respiratory function in obese and nonobese youth e-cigarette users.
Who can participate
Age range21 Years – 25 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* a current e-cigarette user (≥1 vaping bout daily) for at least the past 3 months,
* 21-25 years old,
* willing to abstain from all tobacco and nicotine for at least 12 hours prior to lab sessions,
* willing to complete five lab visits lasting up to 4 hours each,
* able to read and speak English,
* willing to provide informed consent.
Exclusion Criteria:
* self-reported diagnosis of lung disease including asthma or cystic fibrosis
* history of cardiac event or distress within the past 3 months
* history of metabolic disease including thyroid disease or diabetes
* history of orthopedic or neuromuscular problems that preclude exercise
* currently pregnant (determined using urine pregnancy test), planning to become pregnant, delivered a child in the past 6 weeks even if not breastfeeding, or currently breastfeeding
* use of other tobacco products \>10 days in the past month
* current marijuana use \>10 times per month
* currently engaging in a vaping cessation attempt
* ) competitive athlete or individual currently engaged in an exercise training program involving 420min or more (moderate intensity aerobic activity) or 210 min or more (vigorous intensity aerobic activity) per week with the goal of participating in a competitive event or marathon, triathlon, etc. Participants who are engaged in usual physical activity (e.g., walking dog, biking to work, etc.) but not engaged in a "structured exercise training program" will not be excluded.
* plans to leave…
What they're measuring
1
Forced expiratory volume in 1 second
Timeframe: Change from 0 to 35 minutes
2
Functional residual capacity
Timeframe: Change from 0 to 35 minutes
3
Diffusion capacity
Timeframe: Change from 0 to 35 minutes
4
Airway resistance
Timeframe: Change from 0 to 35 minutes
5
Puff count
Timeframe: 35 minutes
6
Average Puff duration
Timeframe: 35 minutes
7
Average Puff volume
Timeframe: 35 minutes
Trial details
NCT IDNCT05869318
SponsorOhio State University Comprehensive Cancer Center