Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy

Inclusion Criteria: * Signed informed consent * Male, aged from 18 to 85 years * Bulbar urethral stenosis ≤ 3 cm. * At least one urethral dilatation or urethrotomy for the bulbar stenosis in the past 24 months before diagnosis of stenosis * Ability to avoid corticoids or immunosuppressive drugs one month after treatment. For any patients with either corticoid or immunosuppressive treatment the physician in charge of this treatment will be contacted and asked to give a written approval for one month cessation of the therapy * Good general health status according to clinical history and a physical examination * BMI \> 18 to insure adequate access to abdominal or other subcutaneous adipose tissue for adipose tissue harvesting Exclusion Criteria: * Urethral stenosis of other location than bulbar * Urethral stenosis length \> 3 cm * Urethral stenosis on reconstructed penis (transgender, post amputation) * Prior perineal or pelvic radiotherapy * Concurrent urinary tract infection without treatment * Concurrent perineal infection * Penile cancer \< 5 years * Current or recent history of abnormal, severe, progressive, uncontrolled infectious, hepatic, haematological, gastrointestinal (except CD), endocrine, pulmonary, cardiac, neurological, psychiatric, or cerebral disease * Congenital or acquired immunodeficiencies * Contraindication to the anaesthetic or surgical procedure * Corticoids or immunosuppressive drugs \> 3 months * Any active viral infection among the following: HIV, …