FB101 Intervention in Women Screened to Have Vaginal Dysbiosis (Dyscover-3)

Inclusion Criteria: * Be able and willing to give written informed consent. * Age between ≥18 to ≤45. * Be generally healthy, as determined by the investigator. * Be a pre-menopausal woman. * Meet the following definition of vaginal dysbiosis: combined copy number of Lactobacillus species crispatus, gasseri, and jensenii measured by qPCR, corresponding to less than 10% total relative abundance of Lactobacillus species crispatus, gasseri, and jensenii as measured by metagenomic sequencing. * Have regular, predictable menstrual cycles of known length or have been amenorrhoeic for at least 3 months due to use of a long-acting progestin or hormonal contraceptives. * Be willing to be asked questions about personal medical, sexual, and behavioural history. * Be willing to undergo two vaginal microbiome transplant procedures. * Be willing to self-collect cervicovaginal secretions and vaginal swab samples. * Be willing to use one of the following effective methods of contraception throughout the clinical study: * Complete abstinence from vaginal intercourse. * Have a male sexual partner who is surgically sterilised prior to the screening visit and is the only male sexual partner for that participant. * Mechanical barrier (condom or diaphragm), or hormone contraception (contraceptive pill, injections, implant or patch). * Be willing to completely abstain from vaginal intercourse and receptive oral sex during the eight days from visit 4 (first FB101 dose) to visit 6 (first foll…