Obinutuzumab in Combination With Lenalidomide in Relapsed or Refractory Follicular Lymphoma in Re… (NCT05846763) | Clinical Trial Compass
RecruitingNot Applicable
Obinutuzumab in Combination With Lenalidomide in Relapsed or Refractory Follicular Lymphoma in Real World Study
China50 participantsStarted 2022-11-01
Plain-language summary
This study is planned to prospectively observe and verify the efficacy and safety of induction therapy with obinutuzumab in combination with lenalidomide followed by maintenance therapy with obinutuzumab and lenalidomide in patients with R/R FL in a real-world setting in a Chinese population.
Who can participate
Age range18 Years
SexALL
See this in plain English?
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Patients must meet the following criteria for study entry::
* Signed Informed Consent Form
* Age ≥ 18 years at enrollment
* At least one prior line of systemic (Stage III-IV) follicular lymphoma therapy
* Relapsed or refractory to front-line anti-lymphoma therapy; refractory is defined as: tumor shrinkage of less than 50% or disease progression after 4 cycles of standard regimen chemotherapy; response to standard regimen chemotherapy, relapse within 24 months; 2 or more relapses, meeting one of the above criteria as refractory lymphoma.
* Conditional treatment with obinutuzumab in combination with lenalidomide
Exclusion Criteria:
* Patients currently participating or planning to participate in any interventional clinical trial
* Any other reason that, in the opinion of the investigator, makes the patient unsuitable for this study
What they're measuring
1
overall response rate(ORR)
Timeframe: 24 weeks
Trial details
NCT IDNCT05846763
SponsorInstitute of Hematology & Blood Diseases Hospital, China