CompletedNot Applicable

Effects of Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Acute Ischemic Stroke

China128 participantsStarted 2023-05-07

Plain-language summary

The purpose of this study was to investigate the effect of repetitive transcranial magnetic stimulation on cerebral autoregulation in patients with acute ischemic stroke.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age ≥ 18 years, both sexes;
✓. Clinically definite diagnosis of acute ischemic stroke;
✓. Baseline National Institute of Health Stroke Scale (NIHSS) score ≤25;
✓. Pre-onset modified Rankin Scale (mRS) score ≤1;
✓. Randomized and initiated transcranial magnetic stimulation within 1 week of onset;
✓. Subject or legal representative agreed to the treatment and signed the informed consent.

Exclusion criteria

✕. Presence of a medical condition such as severe cognitive impairment or mental impairment;
✕. Patients with serious physical diseases or who have had craniocerebral surgery;
✕. Previous history of epilepsy, family history of epilepsy or presence of seizure provoking factors;
✕. Pregnancy or breastfeeding;
✕. The presence of metal foreign bodies near the stimulation site, such as intracranial metal implants, cochlear implants, built-in pulse generators (brain pacemakers, cardiac pacemakers), etc.;
✕. Patients who are unable to complete cerebral autoregulation, or bilateral temporal window penetration poorly;
✕. life expectancy of ≤3 months or inability to complete the study for other reasons;
✕. unwillingness to be followed up or poor treatment compliance;

What they're measuring

phase difference(PD) in degree

Timeframe: 0-5 days

Trial details

NCT IDNCT05843240

SponsorYi Yang

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-03

View on ClinicalTrials.gov More Transcranial Magnetic Stimulation trials