Poor glycaemic control in pregnancy is a major factor leading to obstetric complications and future maternal-offspring diseases. This phenomenon is evidenced in women with type 1 diabetes (T1DM), and is worrisome since it is aggravating the disease burden of this and next generations. Exercise is a promising tool to improve glucose control during pregnancy and thus avoid adverse consequences. The MERIT1D study will explore when is exercise (before or after lunch) more effective to improve postprandial glycaemic control in pregnant and non-pregnant women (of reproductive age) with T1DM, and the mechanisms underlying these metabolic responses.
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Percentage of time spent in the euglycemic range for the 24 hours after each experimental condition
Timeframe: assessed in the study phase 1 (10 days) - at visit nÂş 2, 3, 4 (3 days, 24 hours/day)
Percentage of time spent in the euglycemic range for the 24 hours after each experimental condition
Timeframe: assessed in the study phase 2 (only pregnant women, 10 days) - at visit nÂş 6, 7, 8 (3 days, 24 h/day)