The goal of this clinical research study is to evaluate the safety and tolerability of injecting certain cells that you produce in your bone marrow called mesenchymal stem cells (MSCs) into your salivary glands. Participants will have head and neck cancer that was treated with radiation therapy, and in this study will: * Undergo a collection of bone marrow using a needle; * Donate saliva; * Undergo a salivary gland ultrasound; and, * Complete questionnaires that ask about dry mouth Participants can expect to be in this study for up to 30 months. There is no expanded access program available per this protocol.
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Safety and Tolerability: Determination of Recommended Phase 2 Dose (RP2D)
Timeframe: Up to 1 month post-injection
Safety and Tolerability: Number of subjects with pain >5 on a 0-10 point scale
Timeframe: 1 month post-injection
Safety and Tolerability: Number of Serious Adverse Events
Timeframe: Up to 1 month post-injection
Safety and Tolerability: Number of Treatment-Emergent Pre-Specified Adverse Events
Timeframe: Up to 1 month post-injection