Transcranial Direct Current Stimulation for Post-stroke Fatigue (NCT05816603) | Clinical Trial Compass
RecruitingPhase 2
Transcranial Direct Current Stimulation for Post-stroke Fatigue
United States24 participantsStarted 2023-05-23
Plain-language summary
The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female patients aged \>18 years
* Greater than 3 months from first hemorrhagic or ischemic stroke (subacute to chronic), confirmed through neuroimaging (CT or MRI).
* Fatigue severity score average \>4 (severe fatigue)
* Willingness to remain stable on pharmacologic therapy through the duration of the study.
* Availability of a caregiver, family member, or friend to be present during the administration of the tDCS intervention.
Exclusion Criteria:
* Metal in the head (except mouth) or implanted cranial or thoracic devices (i.e. pacemaker, DBS stimulator)
* History of seizure
* History of moderate to severe traumatic brain injury
* A score of 10 or more on the PHQ-9 or GAD-7 scale, suggestive of moderate to severe depression/anxiety.
* A score of less than 21 on the MoCA suggesting major neurocognitive disorder.
* Signs of skin rash, infection, or laceration in the supraorbital region where the tDCS will be applied.
* Inability to provide informed consent
* Other major neurological, medical, or psychiatric illnesses that could confound results in the opinion of the site investigator.
What they're measuring
1
Mean change from baseline Fatigue Severity Scale - 7 (FSS-7)