Duramesh™ vs Polydioxanone Suture for Laparotomy Closure

Inclusion Criteria: * Age 18 or greater * Abdominal laparotomy 5 cm in length or greater, either midline or non-midline * Isolated ostomy site takedown with or without parastomal hernia * Patient accepts participation and gives informed consent * Patient and investigator signed and dated the informed consent form prior to the index-procedure Exclusion Criteria: * Pregnancy * Presence of clinically recognized hernia at laparotomy site (parastomal hernia noted at time of ostomy site takedown is not an exclusion criterion. Subclinical incidental small hernia \< 1 cm in greatest dimension found at the time of a laparotomy is not an automatic exclusion criterion) * Prior hernia repair at laparotomy site * Use of planar mesh in addition to sutures for closure * CDC IV dirty or infected wound that causes the surgeon to leave the abdominal wall or skin incision open * Life expectancy less than 1 year * Patient is unable / unwilling to provide informed consent * Patient is unable to comply with the protocol or proposed follow-up visits * Patient is enrolled in another abdominal wall study