Sarcopenia characterised by loss of muscle mass, muscle strength and physical performance burdens many older adults since the condition is related to functional decline. Periods of inactivity such as during hospitalisation leads to further functional decline. It has been reported that the loss of muscle mass associated with sarcopenia not only entails a decrease in muscle mass but also changes in muscle architecture. Knowledge on changes in muscle architecture is essential since it is one of the most important determinants on muscle strength and thus physical performance. The main objective of this study is to investigate changes in muscle architecture and physical performance during acute hospitalisation and after discharge in older adults and subsequently the effectiveness of resistance training of the lower limb during acute hospitalisation. If successful, our study could have a great impact on the individual, as well as societal level, due to a better understanding of the factors related to sarcopenia and the prevention of functional decline as a result of hospitalisation.
Age range
65 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change from baseline B-mode ultrasonography
Timeframe: Baseline (day of hospitalisation) to day of discharge from hospital (an average of a week).
Change from baseline 4 meter Gait Speed Test
Timeframe: Baseline (Day of hospitalisation) to day of discharge from hospital (an average of a week).
Change from baseline B-mode ultrasonography
Timeframe: Change from baseline (day of hospitalisation) to 1-month follow-up and 3-months follow-up
Change from baseline 4 meter Gait Speed Test
Timeframe: Change from baseline (day of hospitalisation) to 1-month follow-up and 3-months follow-up