Ultrasound Treatment on Wound Healing Time

Inclusion Criteria: * Male or Female aged 18 or older * Second-degree burn wounds of less than 20% total body surface area (TBSA) * No active wound infection at screening based on clinical criteria * Able to provide written informed consent Exclusion Criteria: * Wounds determined by study clinicians to be ineligible, including those that may inhibit access to the spleen for the ultrasound procedure * Participating in another research study that may affect the conduct of results of this study * BMI \> 30 * Having or exhibiting any of the following: * Previous surgery of the spleen, esophagus, stomach, duodenum, or liver, including splenectomy * End stage renal disease and/or uremia * Active malignancy * Previous leukemia and/or lymphoma * Human immunodeficiency virus infection or AIDS * Rheumatoid arthritis or other immune-mediated diseases (e.g., inflammatory bowel disease * Arrythmias, including but not limited to, atrial fibrillation, atrial flutter, clinically significant bradycardia, ventricular arrhythmias, and A-V block * Implanted pacemaker or cardioverter/debribrillator * History of unstable angina, angioplasty or coronary arterial by-pass grafting surgery * History of stroke or TIA * Untreated thrombosis or bleeding disorders * Currently implanted vagus nerve stimulator * Currently implanted spinal cord stimulator or other chronically implanted electronic device * Receiving oral, topical, rectal, or parenteral corticosteroids in an unsta…