Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine f… (NCT05788393) | Clinical Trial Compass
CompletedPhase 4
Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic Cholecystectomy
Egypt64 participantsStarted 2024-04-01
Plain-language summary
Opioid sparing analgesia: Continuous intraoperative infusion of dexmedetomidine versus lidocaine for laparoscopic cholecystectomy, a randomized double-blind clinical trial.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient's status ASA status-I and II.
* Patients age above 18 years old.
* Patients scheduled for laparoscopic cholecystectomy.
Exclusion Criteria:
* Patient refusal.
* Patients with known allergy to dexmedetomidine or lidocaine.
* Patients with significant hepatic dysfunction.
* Patients with severe renal disease.
* Patients with chronic pain.
* Regular use analgesics, antidepressants or opioids in last month.
* Any known convulsive disorder.
* Significant heart disease.
* Morbid obesity (BMI\>35).
* Patients with autoimmune disease
* Patients on corticosteroid therapy
* Pregnancy
* Breast feeding
* Woman under hormonal treatment