Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel (NCT05773911) | Clinical Trial Compass
UnknownNot Applicable
Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel
Norway40 participantsStarted 2023-03-23
Plain-language summary
In the here suggested study, the aim is to test non-surgical treatment of advanced periodontal disease with a chitosan brush with or without chitosan gel in patients with advanced periodontal disease having responded poorly to a more conventional treatment strategy, with the aim to hinder the progression of bone loss around the teeth.
Who can participate
Age range19 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
Patients with at least 3 teeth but less than 8 teeth with advanced periodontal attachment loss.
Clinical Attachment Loss (CAL) ≥5 mm, probing pocket depth (PPD) ≥5mm and ≤8 mm and inflammation as demonstrated by a modified Bleeding on Probing (BoP) grade 2 (line) or 3 ("spontaneous").
Exclusion criteria:
* Ongoing radiotherapy, ongoing chemotherapy, pregnant or nursing patients, prosthetic factors making access to clinical measurements impossible
* Poor oral hygiene with plaque at \>20% of the surfaces
* Periodontal pockets reaching to the apex of teeth.
* Teeth with active peri-apical pathology
* Teeth with root resorption as seen on radiographs
* Teeth with prosthodontic technical complications should be excluded or treated before inclusion (e.g., overhangs, open contacts with food impaction)
* Teeth with pockets from other reasons than periodontal disease
* Teeth with traumatic occlusion should be excluded or treated before inclusion (i.e., fremitus)
* Patients diagnosed with Periodontal disease grade C i.e., rapid rate of progression
* Sites in direct proximity with site(s) where patient places snuff (Copenhagen) will be excluded