Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel (NCT05773911) | Clinical Trial Compass
UnknownNot Applicable
Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel
Norway40 participantsStarted 2023-03-23
Plain-language summary
In the here suggested study, the aim is to test non-surgical treatment of advanced periodontal disease with a chitosan brush with or without chitosan gel in patients with advanced periodontal disease having responded poorly to a more conventional treatment strategy, with the aim to hinder the progression of bone loss around the teeth.
Who can participate
Age range
19 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
Patients with at least 3 teeth but less than 8 teeth with advanced periodontal attachment loss.
Clinical Attachment Loss (CAL) ≥5 mm, probing pocket depth (PPD) ≥5mm and ≤8 mm and inflammation as demonstrated by a modified Bleeding on Probing (BoP) grade 2 (line) or 3 ("spontaneous").
Exclusion criteria:
* Ongoing radiotherapy, ongoing chemotherapy, pregnant or nursing patients, prosthetic factors making access to clinical measurements impossible
* Poor oral hygiene with plaque at \>20% of the surfaces
* Periodontal pockets reaching to the apex of teeth.
* Teeth with active peri-apical pathology
* Teeth with root resorption as seen on radiographs
* Teeth with prosthodontic technical complications should be excluded or treated before inclusion (e.g., overhangs, open contacts with food impaction)
* Teeth with pockets from other reasons than periodontal disease
* Teeth with traumatic occlusion should be excluded or treated before inclusion (i.e., fremitus)
* Patients diagnosed with Periodontal disease grade C i.e., rapid rate of progression
* Sites in direct proximity with site(s) where patient places snuff (Copenhagen) will be excluded
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.