Assessment of Bone Quality After Socket Preservation Using Sodium Alendronate Gel Compared to Sti… (NCT05771038) | Clinical Trial Compass
UnknownEarly Phase 1
Assessment of Bone Quality After Socket Preservation Using Sodium Alendronate Gel Compared to Sticky Bone
Egypt32 participantsStarted 2023-04
Plain-language summary
The aim of study to evaluate the quality and quantity of the formed bone after socket preservation using sticky bone versus alendronate gel
Who can participate
Age range16 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
\- defective class III sockets
* Patients with non-restorable teeth extracted sites
* Patients who have given their consent for this trial.
* Both genders males and females will be included.
Exclusion Criteria:
* Patients should not have taken drugs, especially bisphosphonates or drugs altering bone metabolism, within 2 months before the inclusion in the study.
* Subjected to irradiation in the head and neck area less than 1 year before implantation.
* Patients having history of allergy to any drugs.
* Patients who have a history of any concomitant major known medical problem and/or ongoing pharmacologic treatments
* Untreated periodontitis.
* Poor oral hygiene and motivation.
* Uncontrolled diabetes.
* Pregnant or nursing.
* Substance abuse.
* Psychiatric problems or unrealistic expectations.
* Severe bruxism or clenching.
* Immunosuppressed or immunocompromised.
* Treated or under treatment with intravenous amino-bisphosphonates.
* Active infection or severe inflammation in the area intended for implant placement.
* Unable to open mouth sufficiently to accommodate the surgical tooling.
* Patients participating in other studies, if the present protocol could not be properly followed.
* Referred only for implant placement or unable to attend a 5-year follow-up.
What they're measuring
1
Histomorphometric analysis
Timeframe: 3 month from the socket preservation procedure