The goal of this clinical trial is to investigate the effect of propolis administration on dysmenorrhea in endometriosis patient. the main questions it aims to answer are: * Does the propolis administration reduce symptoms of dysmenorrhea in endometriosis? * Does the propolis administration reduce the amount of oxidative stress biomarkers in endometriosis? * Does the propolis administration reduce the amount of Inflammatory biomarkers in endometriosis? Participants will be given an intervention in the form of propolis at a dose of 1 drop per 10 kilogram of body weight per administration, twice a day. there will be a control group that will be given an intervention in the form of a placebo containing 70% caramel alcohol dye solution.
Age range
20 Years – 49 Years
Sex
FEMALE
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Malondialdehyde (MDA)
Timeframe: week 0
Malondialdehyde (MDA)
Timeframe: week 4
Malondialdehyde (MDA)
Timeframe: week 12
Superoxide dismutase (SOD)
Timeframe: week 0
Superoxide dismutase (SOD)
Timeframe: week 4
Superoxide dismutase (SOD)
Timeframe: week 12
interleukin 6
Timeframe: week 0
interleukin 6
Timeframe: week 4
interleukin 6
Timeframe: week 12
tumor necrosis factor alpha (TNF alfa)
Timeframe: week 0
tumor necrosis factor alpha (TNF alfa)
Timeframe: week 4
tumor necrosis factor alpha (TNF alfa)
Timeframe: week 12
pain scale
Timeframe: week 0
pain scale
Timeframe: week 4
pain scale
Timeframe: week 12
Glutathione
Timeframe: week 0
Glutathione
Timeframe: week 4
Glutathione
Timeframe: week 12
8-hydroxy-2-deoxyiguanosine (8-OHdG)
Timeframe: week 0
8-hydroxy-2-deoxyiguanosine (8-OHdG)
Timeframe: week 4
8-hydroxy-2-deoxyiguanosine (8-OHdG)
Timeframe: week 12