An Open Comparative Study of the Effectiveness and Incomparable Study of the Immunogenicity and Safety of the Vaccine (CoviVac) for Adults Aged 60 Years and Older

Inclusion Criteria: Volunteers must meet the following inclusion criteria: Type of participants • Healthy volunteers or volunteers with a history of stable diseases that do not meet any of the criteria for non-inclusion in the study. Other inclusion criteria * Written informed consent of volunteers to participate in a clinical trial * Volunteers who are able to fulfill the Protocol requirements (i.e., fill out a self-observation Diary, come to control visits). Exclusion Criteria: SARS-CoV-2 infection • A case of established COVID-19 disease confirmed by PCR and/or ELISA in the last 6 months. Diseases or medical conditions * Serious post-vaccination reaction (temperature above 40 C, hyperemia or edema more than 8 cm in diameter) or complication (collapse or shock-like condition that developed within 48 hours after vaccination; convulsions, accompanied or not accompanied by a feverish state) to any previous vaccination. * Burdened allergic history (anaphylactic shock, Quincke's edema, polymorphic exudative eczema, serum sickness in the anamnesis, hypersensitivity or allergic reactions to the introduction of any vaccines in the anamnesis, known allergic reactions to vaccine components, etc.). * Guillain-Barre syndrome (acute polyradiculitis) in the anamnesis. * The axillary temperature at the time of vaccination is more than 37.0 ° C. * Acute infectious diseases (recovery earlier than 4 weeks before vaccination) according to anamnesis. * Donation of blood or plasma (in …