Several high-altitude destinations recommend their visitors to avoid caffeine, theoretically due to the associated diuresis which could contribute to acute mountain sickness. There is however no direct evidence for this association. In fact, caffeine ingestion is known to improve exercise performance at sea level, and may therefore help mountaineers during expeditions. Sport science research is largely conducted in male participants, and the findings from these studies are assumed to apply to the female population. Given the known sex differences in body composition, hormones, and other physiological factors, this may not be appropriate. It is therefore important to conduct research in women, to allow for female-specific recommendations.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Peak oxygen uptake
Timeframe: Immediately prior to volitional exhaustion during the incremental exercise test
Maximal aerobic power
Timeframe: At the instant of volitional exhaustion during the incremental exercise test
Peak minute ventilation
Timeframe: Immediately prior to volitional exhaustion during the incremental exercise test
Peak heart rate
Timeframe: Immediately prior to volitional exhaustion during the incremental exercise test
Muscle oxygenation nadir
Timeframe: Immediately prior to volitional exhaustion during the incremental exercise test
Peak blood lactate concentration
Timeframe: Immediately after volitional exhaustion during the incremental exercise test