The study will evaluate pain and recovery after a single injection axillary plexus block combined with an intravenous dose of 0.1 mg/kg dexamethasone in ambulatory patients undergoing upper extremity bone surgery. The investigators will try to identify the risk factors involved in a decrease in the efficacy of dexamethaxone for the prevention of RP. The hypotheses are that : * The interindividual variability may modulate the preventive effect on "rebound pain" after axillary block, of pre-incisional administration of an anti-inflammatory dose of dexamethasone (0.1 mg/kg max 10 mg). * Patients with increased preoperative anxiety or underlying catastrophizing will experience more postoperative pain as the axillary PNB dissipates. * Elevated preoperative salivary lipocortin 1 and cortisol levels result in a lesser preventive effect of dexamethasone on the development of rebound pain.
Age range
18 Years – 75 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Impact of sexe on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year
Impact of BMI on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year
Impact of preoperative anxiety levels on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year
Impact of preoperative levels of pre-existing catastrophizin on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year
Impact of preoperative levels of central sensitization on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year
Impact of baseline levels of Lipocortin 1 and cortisol on the efficacy of DEXA on the occurrence of RP
Timeframe: Through study completion, an average of 1 year