The purpose of this study is to assess the safety and immunogenicity of mRNA-1365, an mRNA vaccine targeting respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) and mRNA-1345, an mRNA vaccine targeting RSV, in participants aged 5 months to \<24 months.
Age range
5 Months – 24 Months
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Main Study: Number of Participants with Solicited Local and Systemic Adverse Reactions (ARs)
Timeframe: Up to Day 120 (7 days after each injection)
Main Study: Number of Participants with Unsolicited Adverse Events (AEs)
Timeframe: Up to Day 141 (28 days after each injection)
Main Study: Number of Participants with Medically-Attended Adverse Events (MAAEs)
Timeframe: Day 1 through Day 730
Main Study: Number of Participants with Adverse Event of Special Interests (AESIs), Serious Adverse Events (SAEs) and Adverse Events Leading to Discontinuation
Timeframe: Day 1 through Day 730
Part B Extension: Number of Participants with MAAEs, AESIs and SAEs
Timeframe: Day 1 of the Extension to end of study (EoS) (up to 3 years)
Part B Extension: Number of Participants with Lower Respiratory Tract Illness (LRTI), Severe LRTI, Very Severe LRTI, and Hospitalizations Associated with RSV or hMPV
Timeframe: Day 1 of the Extension to EoS (up to 3 years)