Frontal and Parietal Contributions to Proprioception and Motor Skill Learning (NCT05739994) | Clinical Trial Compass
CompletedNot Applicable
Frontal and Parietal Contributions to Proprioception and Motor Skill Learning
United States118 participantsStarted 2023-06-09
Plain-language summary
The purpose of this study is to understand how the different regions of the brain affect our sense of limbs in space (proprioception) and in turn our hand movements (motor skill learning). This information might help us one day to generate better rehabilitation protocols to help patients with movement deficits.
Who can participate
Age range18 Years – 45 Years
SexALL
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Inclusion Criteria:
* Potential subjects must be between the ages of 18-45 years old and right-handed.
* We will only test right-handed individuals.
* We will only include individuals who report being free of Covid symptoms in week preceding testing.
Exclusion Criteria:
* Current vision problems, other than needing glasses or contacts.
* Subjects will also be excluded if they currently suffer from frequent severe headaches, glaucoma, heart or respiratory disease, hypertension, psychiatric conditions, or learning or attention conditions.
* They will also be excluded for current or past: visual, hearing, or balance impairments; stroke, seizure/epilepsy (including family history), or severe head trauma; fainting; or diabetes.
* Subjects will be excluded for metal implants in the head other than titanium; cochlear implants; implanted neurostimulator; cardiac pacemaker; intracardiac lines; or a medication infusion device.
* Because TMS does not penetrate deeply into the head, we cannot test subjects whose hair does not permit contact between the TMS coil and the scalp. We will therefore exclude subjects with dreadlocks, weaves, or hair extensions.
* To protect the data from extraneous peripheral influences, we will also exclude subjects who have had serious injury to the bones, joints, or muscles of either hand or arm, and have not fully recovered. For the purpose of this study, "fully recovered" means they no longer notice any pain, weakness, or loss of sensation in the injure…
What they're measuring
1
Motor Skill
Timeframe: Assessed 4 times during the 2-hour main session: Pre-cTBS ("Pre"), immediately post-cTBS ("Post1"), after 40 trials of maze-tracing practice ("Post2"), and after 80 trials of maze-tracing practice ("Post 3").
2
Proprioception
Timeframe: Assessed at 2 timepoints during the 2-hour main session: pre-cTBS ("Pre") and post-cTBS ("Post").