CompletedNot Applicable

Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth

Egypt28 participantsStarted 2024-07-01

Plain-language summary

The aim of this study is to compare the effect of antimicrobial-corticosteroid mixture and cryotherapy as final root canal irrigating solutions on post-instrumentation pain in single-canal teeth with necrotic pulps.

Who can participate

Age range18 Years – 50 Years

SexALL

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Inclusion criteria

✓. Patients in good physical health; American Society of Anesthesiologists class I or II.
✓. Patients whose age ranges between 18 and 50 years.
✓. Male and female patients.
✓. Patients having a single canal-tooth with necrotic pulp.
✓. Patients who can understand the number rating scale (figure).
✓. Patients who accept to participate in the trial and can sign the informed consent (figure).

Exclusion criteria

✕. Pregnant females.
✕. Patients with swelling.
✕. Patients whose tooth is non-restorable.
✕. Teeth with open apices.
✕. Teeth with radiographic evidence of root resorption.

What they're measuring

Postinstrumentation pain

Timeframe: At 6 hours after the 1st visit

Postinstrumentation pain

Timeframe: At 12 hours after the 1st visit

Postinstrumentation pain

Timeframe: At 24 hours after the 1st visit

Postinstrumentation pain

Timeframe: At 48 hours after the 1st visit

Trial details

NCT IDNCT05739682

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-30

View on ClinicalTrials.gov More Dental Pulp Necrosis trials