The purpose of this study is to validate previously developed physical function-clustered specific machine-learned accelerometer algorithms to estimate total daily energy expenditure (TDEE) in individuals with general movement and functional limitations.
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Accuracy of accelerometer derived estimations of total daily energy expenditure (TDEE, kcals/day).
Timeframe: 8-10 days monitoring
Precision of accelerometer derived estimations of total daily energy expenditure (TDEE, kcals/day).
Timeframe: 8-10 days monitoring
Total Daily Energy Expenditure (TDEE) (via DLW)
Timeframe: pre-dose; 4 hours and 5 hours post-dose, and 8-10 days post-dose