Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impair… (NCT05735041) | Clinical Trial Compass
UnknownNot Applicable
Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment
China224 participantsStarted 2023-01-18
Plain-language summary
In this study, a multicentre, double-blind, randomized controlled study based on cognitive training was conducted in patients with coronary heart disease and cognitive impairment but without dementia， to evaluate the effectiveness of computer-based digital therapy in improving the cognitive function of such patients.
Who can participate
Age range50 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Over the age of 50;
✓. Completion of more than 6 years of education;
✓. Patients with coronary artery disease confirmed by coronary CT angiography or coronary angiography;
✓. Chief complaint of cognitive decline within 1 year;
✓. The average score of any cognitive domain in processing speed, situational memory, working memory and visual space measured by the Basic Cognitive Ability Test (BCAT) is less than 1 SD compared with the normal population;
✓. Agree to be randomized to cognitive function tests and cognitive training and be able to receive follow-up as required.
Exclusion criteria
✕. Previous definite diagnosis of dementia or brief Mental State Examination Scale (MMSE) \< 24 points;
✕. Cognitive dysfunction caused by cranial trauma, cranial tumor, Parkinson's disease, schizophrenia, Alzheimer's disease, anxiety and depression, and other neuropsychiatric diseases;
✕. Deaf and mute or other reasons cannot communicate normally;
✕. Binge drinking or taking drugs (antihistamines, antipsychotics) that affect cognitive function;
✕. Unable to master the use of cognitive training equipment after two 1-hour training instructions each time;
✕
What they're measuring
1
Global cognitive function change measured by BCAT in 12 weeks