We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.
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Medication adherence based on medication level variability index
Timeframe: 12 weeks
Directly observed medication adherence
Timeframe: 1 weeks
Late Acute Rejection
Timeframe: 6 months post-intervention
Hospitalization
Timeframe: 6 months post-intervention
Patient Activation Measure
Timeframe: Pretest at enrollment and posttest at 12 weeks
Patient Assessment of Chronic Illness Care (PACIC)
Timeframe: Pretest at enrollment and posttest at 12 weeks
Self-reported user satisfaction with the DOT app
Timeframe: Pretest at enrollment and posttest at 12 weeks
Engagement metrics
Timeframe: Pretest at enrollment and posttest at 12 weeks
PedsQL 3.0 Transplant Module (PedsQL-TM)
Timeframe: Pretest at enrollment and posttest at 12 weeks
Adolescent Medication Barriers Scale (AMBS)
Timeframe: Pretest, posttest
Parent Medication Barriers Scale (PMBS)
Timeframe: Pretest at enrollment and posttest at 12 weeks