Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting

Inclusion Criteria: * At least 18 years of age, woman, pre-menopausal, non-pregnant with clinical signs of urinary tract infection and nitrite positive urine. Exclusion Criteria: * Contraindications include hypersensitivity to gentamicin or other aminoglycosides. * Patients younger than 18 years of age. * Pregnant or post-menopausal patients. * Patients without symptoms of UTI, nitrite negative urine, or any patient with working diagnosis of complicated UTI such as pyelonephritis or any patient catheterized. * ANY history of pre-existing renal impairment. * Patient that has any listed or reports taking ANY nephrotoxic or wit drug-drug interaction medication in the past 7 days (see Appendix 5). * ANY history of hearing loss, tinnitus, or vertigo. * ANY patient that has received general anesthesia or neuromuscular blockade in past 7 days. * Patients with ANY history of neuromuscular disorders including: myasthenia gravis, amyotrophic lateral sclerosis, muscular dystrophy, botulism, congenital myasthenic syndromes, congenital myopathies, myositis, Lambert-Eaton syndrome, mitochondrial myopathy, myotonic dystrophy, neuromyotonia, or peripheral neuropathy. * Patients with ANY history of thrombocytopenia. * Patient that has any listed or reports taking ANY anticoagulants in the past 7 days.