Self- Administered Acupressure for Diarrhea Predominant Irritable Bowel Syndrome

Inclusion Criteria: * Diagnosed with diarrhea irritable bowel syndrome symptoms following Rome IV diagnostic criteria * Agreed to be on a fixed dose of the pharmacological therapy throughout the study Exclusion Criteria: * Patients with severe lesions in major organs such as the heart, liver, and kidney, hematopoietic diseases, or tumors * Eating disorders * History of major abdominal surgery * History of neurological and mental illness * Usage of other treatment rather than the medical treatment regularly 2 weeks before randomization and throughout the study * Previous history of drug or alcohol abuse 6 months before randomization * Pregnant and lactating women. * Patient reporting of adequate relief of their irritable bowel syndrome symptoms the week preceding the randomization * Patient has too mild symptoms ( obtaining less than 75 on Irritable bowel syndrome symptoms severity scale at the baseline assessment) * Currently participating in other clinical trials