The primary purpose of the study is to assess the shedding, transmission, and genetic stability of the live-attenuated RSVt vaccine after each intranasal vaccination (56 days apart) in infants and toddlers 6 to \< 24 months of age.
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Percentage of Placebo Receiving Pediatric Participants With Vaccine Virus Detected in Nasal Swabs After the First Vaccination
Timeframe: Pre-vaccination on Day 1 and post-vaccination on Days 4, 8, 11, 15, 18 and 22
Titer of Vaccine Virus Shedding in All Pediatric Participants Detected in Nasal Swabs
Timeframe: Pre-vaccination on Day 1 and post-vaccination on Days 4, 8, 11, 15, 18, 22, 64 and 71
Percentage of Placebo Receiving Pediatric Participants With Detected Shedding Who Showed Any Genetic Sequence Variation After Each Vaccination
Timeframe: Up to 21 days after each vaccination (Day 1 to Day 22 and Day 57 to Day 78)